penetrating - meaning and definition. What is penetrating
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What (who) is penetrating - definition

SHORT POLYCATIONIC SEQUENCES
Polycation conjugate; Cell penetrating peptide; Cell-penetrating peptides; Protein transduction domain; Cell Penetrating Peptide
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penetrating      
1.
A penetrating sound is loud and usually high-pitched.
Mary heard the penetrating bell of an ambulance...
= piercing
ADJ
2.
If someone gives you a penetrating look, it makes you think that they know what you are thinking.
He gazed at me with a sharp, penetrating look that made my heart pound.
= piercing
ADJ: usu ADJ n
3.
Someone who has a penetrating mind understands and recognizes things quickly and thoroughly.
...a thoughtful, penetrating mind...
ADJ: usu ADJ n
penetrating      
adjective (of a sound) clearly heard through or above other sounds.
penetrating      
a.
1.
Sharp, subtle, piercing, penetrative, permeating.
2.
Discerning, intelligent, sagacious, sharp-witted, clear-sighted, acute, keen, quick, shrewd, keen-sighted.

Wikipedia

Cell-penetrating peptide

Cell-penetrating peptides (CPPs) are short peptides that facilitate cellular intake and uptake of molecules ranging from nanosize particles to small chemical compounds to large fragments of DNA. The "cargo" is associated with the peptides either through chemical linkage via covalent bonds or through non-covalent interactions.

CPPs deliver the cargo into cells, commonly through endocytosis, for use in research and medicine. Current use is limited by a lack of cell specificity in CPP-mediated cargo delivery and insufficient understanding of the modes of their uptake. Other delivery mechanisms that have been developed include CellSqueeze and electroporation.

CPPs typically have an amino acid composition that either contains a high relative abundance of positively charged amino acids such as lysine or arginine or has sequences that contain an alternating pattern of polar, charged amino acids and non-polar, hydrophobic amino acids. These two types of structures are referred to as polycationic or amphipathic, respectively. A third class of CPPs are the hydrophobic peptides, containing only apolar residues with low net charge or hydrophobic amino acid groups that are crucial for cellular uptake.

Transactivating transcriptional activator (TAT), from human immunodeficiency virus 1 (HIV-1), was the first CPP discovered. In 1988, two laboratories independently found that TAT could be efficiently taken up from the surrounding media by numerous cell types in culture. Since then, the number of known CPPs has expanded considerably, and small molecule synthetic analogues with more effective protein transduction properties have been generated.

A recent discovery found that Papillomaviridae, such as the human papillomavirus, use CPPs to penetrate the intracellular membrane to trigger retrograde trafficking of the viral unit to the nucleus.

Pronunciation examples for penetrating
1. practically penetrating the wall.
ted-talks_1853_GianGiudice_2013X-320k
2. eventually penetrating a cell
ted-talks_1783_MohamedHijiri_2013X-320k
3. And it's very penetrating.
Beautiful Whale _ Bryant Austin _ Talks at Google
4. quite penetrating questions, which--
Into the Magic Shop _ James Doty _ Talks at Google
5. THERE'S NOTHING PENETRATING THE SKIN.
How Becoming Part Computer Made Me More Human _ Michael Chorost _ Talks at Google
Examples of use of penetrating
1. Almost instantly, his penetrating revelations were producing angry reactions.
2. "Reid promised a penetrating look at criminal justice policy.
3. You have penetrating wounds, indented stone, debris, glass or metal.
4. Newspaper rich lists go some way towards penetrating the veil.
5. Gerontophobia is penetrating, instinctive and pretty well universal.